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Additionally, administration of a pharmacological dose of vitamin K (menaquinone-4 or phylloquinone) mitigated tissue damage associated with ferroptosis induced by ischemia-reperfusion injury and tissue-specific conditional Gpx4 knockout [52,157]
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A recent open-label study demonstrated that transcranial magnetic stimulation increased GSH levels in the left dorsolateral prefrontal cortex in 18 unmedicated patients with MDD, although there was no correlation between the GSH increase and the decrease in depression severity after treatment [26]
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