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TPS is a secretion pathway that appears to play diverse roles in several Gram-negative bacteria and includes a large secreted protein (generally referred to as TpsA) and a channel-forming β barrel outer membrane activator/transport protein (TpsB) (Henderson et al., 2004
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This causes β-catenin to accumulate in the cytoplasm and then translocate to the nucleus, where it can interact with TCF/LEF transcription factors
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