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[27] Under the current chemotherapy treatments, about 70% of adult AML patients have achieved complete remission, while only about 20% of patients have achieved long-term disease-free survival, for most of the deceased patients have died of refractory or recurrent AML

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while respiratory viral infections cause antioxidant enzyme expression/activity inhibition associated with reduced Nrf2 nuclear localization, decreased cellular levels and reduced ARE-dependent gene transcription (Komaravelli and Casola, 2014)

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