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Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers - ScienceDirect
Manipulating methylation potential has, in principle, epigenetic implications, and NNMT’s biology intersects with cancer pathways in complex and tissue-dependent ways — in some cancers NNMT is overexpressed and pro-tumorigenic, which is a reason for caution rather than alarm, but a reason that can only be resolved by real safety studies
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[DOI] [PubMed] [Google Scholar] Authier N., Balayssac D., Marchand F., Ling B., Zangarelli A., Descoeur J., Coudore F., Bourinet E., Eschalier A
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