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DIA vs DDA in Phosphoproteomics: Which One Should You Use? - Creative Proteomics
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The widely repeated claim that Dihexa is "seven orders of magnitude more potent than BDNF" originates from that flagged McCoy paper and reflects an assay-specific in-vitro spine-density measurement — picomolar Dihexa versus nanomolar BDNF in one assay — not a millions-fold advantage in a living brain
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