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Reduced thalamic glutathione in migraine: a MEGA-PRESS spectroscopy study | The Journal of Headache and Pain | Springer Nature Link
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The effect of metformin on promoting degradation of HIF-1α can also inhibit the allosteric activator of phosphofructokinase-1 6-phosphofructose-2-kinase/fructose-2, 6-bisphosphatase 3 (PFKFB3), downregulating the expression of PFK1 mediated by PFKFB3 to inhibit glycolysis and cancer cell proliferation (88)
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