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A large 2026 study found that colon cancer patients with very high B12 levels survived a median of around five years, compared with nearly eleven years for those with normal levels

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Once stores are replenished, maintenance injections can be spaced much further apart — commonly every 2 to 3 months rather than more frequently Cyanocobalamin is cleared faster, so maintenance requires more frequent injections For that reason hydroxocobalamin is the preferred form for long-term maintenance in many countries

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