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Frontiers | Microbial detoxification of mycotoxins in food

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NMR validation of 1907 interactions and circular dichroism To validate the binding mode of 1907 and map its interactions with the FAT domain, we performed heteronuclear single quantum coherence-nuclear magnetic resonance (HSQC-NMR) chemical shift perturbation (CSP) studies with 15 N labeled recombinant FAT protein and titrating amounts of 1907 from 100 nM to 200 µM (Fig