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192 A study involving 591 elderly men and 307 elderly women living in community or assisted living facilities found higher DHEA-S levels were correlated with lower likelihood of frailty in both male and female participants, and the correlation was stronger in those with low BMI

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and (iii) TPD’s catalytic pharmacology—one degrader molecule eliminating multiple target copies—offers sustained target suppression at sub-stoichiometric concentrations, a feature particularly attractive for overcoming high-burden or high-turnover immunosuppressive proteins