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Likewise, REDEFINE 9, announced alongside REIMAGINE 5, used placebo as its comparator
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The C-terminal residues form a set of inter- and intra-molecular, antiparallel β-bridges between hTrxR1 residues 495′ hTrxR1 to 499′ hTrxR1 and hTrx1 residues 72 hTrx1 to 75 hTrx1 as well as a mixed disulphide between U498C′ hTrxR1 and Cys32 hTrx1 (Fig
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