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The 12mg cohort achieved the highest mean body weight reduction at -24.2% — exceeding all published results for semaglutide (approximately -16% in the STEP trials) and tirzepatide (approximately -22.5% in SURMOUNT-1) at their respective maximum doses
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[33] Adults aged 65 years and older constitute the most rapidly growing population in the United States, and functional capacity in physical (non-psychological) domains has been shown to decline with age
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