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PMID: Summary Keywords adenosine, CD38, daratumumab, immunosuppression, immunotherapy, inosine, isatuximab, multiple myeloma Citation Horenstein AL, Frerichs KA, Faini AC, van de Donk NWCJ and Malavasi F (2026) Modulating CD38 enzymatic activity during antibody-based immunotherapy in multiple myeloma: a basic science perspective
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Four cryo-electron microscopy structures at 2.42 to 2.75 angstrom resolution show the synthetic pairs sitting in the enzyme’s active site in standard Watson-Crick geometry, the same shape natural pairs take
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