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Before taking a B12 shot, tell your doctor if you: Are allergic to B12, cobalt or any multivitamin combinations Have vision issues or Leber’s disease (a genetic condition that causes vision loss) Have any infections Have been diagnosed with folic acid deficiency or iron deficiency Are pregnant, breastfeeding, or planning to get pregnant Are taking any supplements, including herbal supplements Are taking any medications, such as folic acid, methotrexate, chloramphenicol, colchicine, para-aminosalicylic acid (PAS), or pyrimethamine Have liver or kidney disease Have a drinking problem Health News Eliminating Ultra-Processed Food From School Cafeterias Will Be Costly, Complicated, Study Warns 1 In 5 Seniors At Risk For Dangerous Drug Interactions Exercise A Solid Prescription For Pain, Review Reports Loneliness, Isolation Can Strip Away Years Of Healthy Life, Large Study Finds 165,000+ Pounds Of Pork, Beef And Goat Recalled Over USDA Inspection Mark More Health News » RxList

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Larger total daily amounts use IV instead, because 5 mL (about 1,076 mg) is the practical IM limit