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Significance of Melatonin in the Regulation of Circadian Rhythms and Disease Management | Molecular Neurobiology | Springer Nature Link

5.1 Chronic stress and hippocampal synaptic plasticity Synaptic plasticity refers to changes in synaptic structure and function in response to neuronal activity and serves as a fundamental neurobiological basis for learning and memory (Takeuchi et al., 2014)

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In a nationwide population-based study, 2957 children and adolescents with iron deficiency anemia (IDA) showed a higher risk than their matched controls of developing unipolar depressive disorder, BD, anxiety disorder, ASD, ADHD, tic disorder, and developmental delay, with a higher risk of developing BD and tic disorder in female patients with IDA [112]