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It is worth mentioning that ACD remains a classical type IV T cell-mediated allergy, and, consequently, it presents with the activation of the innate immune system and adaptive immune response, which is opposite to ICD, in which the adaptive immune response is not activated [149]
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39 Benzene oxide, another carcinogen, can be detoxified in the body by GSTT1 through its reaction with GSH, ultimately leading to its excretion in urine as S-phenylmercapturic acid
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