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Often referred to as an “eye stroke,” NAION is a rare but serious condition where blood flow to the optic nerve is suddenly reduced, leading to painless and irreversible vision loss

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found that in colon cancer, Gln deprivation stimulates p53 activation and promotes the expression of the aspartate/glutamate transporter SLC1A3, thereby promoting glutamate, Gln and nucleotide synthesis, maintaining electron transport chain and tricarboxylic acid cycle activity