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Nutritional deficiencies after bariatric surgery | Nature Reviews Endocrinology

The energy expenditure finding belongs to the 2014 knockdown work, where NNMT was knocked down in mouse tissues and no small-molecule compound was given

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FIGURE 1 Alpha-Synuclein Pathology in Parkinson’s Disease Alpha-synuclein is a neuronal protein found at synapses and is abundantly found in the brain (Figure 1A) and is associated with the neuropathology observed in PD and related neurodegenerative disorders (e.g., Lewy Body Disease and Multiple System Atrophy), predominantly through the formation of aberrant aggregates that may disrupt cellular homeostasis, synaptic function, and induce neuronal degeneration (Spillantini et al., 1997, 1998