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Both FHL3 patients and the Unc13d Jinx mouse strain lack Munc13–4 and have robust granule-release defects and bleeding diatheses
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We estimate the CY 2026 PFS qualifying APM CF to be $33.5675 which reflects a 0.49 percent positive budget neutrality adjustment required under section 1848(c)(2)(B)(ii)(II) of the Act and the 0.75 percent update adjustment factor specified under section 1848(d)(20) of the Act
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